SILYMARIN (Milk Thistle)
Description: The liver is the organ responsible
for the metabolism of carbohydrates, fats, proteins, storage of vitamins and minerals and most importantly detoxifying the
body. If normal liver function is altered or decreased (due to toxins or free radicals), proper metabolism of nutrients and
blood purifying will be impaired. Any toxin or free radical that enters the body has the potential to cause damage to all
the cells of the body, especially the cells of the liver. Silymarin is a flavonoid antioxidant isolated from milk thistle
(fruit of Silybum marrium) that works to counteract the detriment that occurs to the liver during the metabolism of toxins
and free radicals. Silymarin has also been shown in clinical trials to be an effective in supporting prostate health. Animal
studies indicate silymarin may benefit cholesterol metabolism. Silymarin (Milk Thistle) Silymarin
(Milk Thistle) Silymarin (Milk Thistle) Milk thistle is a flower, more specifically a member of the aster family. Its seeds and roots have been used for
an assortment of medical purposes for thousands of years. Three biochemicals of interest have been isolated from the milk
thistle: silychristine, silydianin, and silybin. The mixture of these three substances is called “silymarin.”
Silymarin has been traditionally used in the treatment of liver. The biological mechanism of action is yet unknown but several
theories exist: - May offer some protective benefit if you are taking
medication that can harm the liver.
- Helps raise glutathione levels Milk
thistle in Latin is Silybum marianum. It supports liver function by raising protective glutathione levels.
- Silymarin may control cell membrane permeability which means that silymarin may control what
substances actually enter the interior of a cell.
- Silymarin may inhibit
chemical pathways leading to inflammatory biochemicals.
- Silymarin may
have free radical scavenging properties which means that it may absorb harmful reactive atoms that could damage other molecules.
- Silymarin may increase protein production by liver cells.
- Silymarin may stabilize mast cells (cells containing inflammatory granules).
- Silymarin in higher doses increases the flow of bile.
HOW
THIS MEDICATION IS USED The most scientific information concerning the use
of silymarin regards Amanita mushroom poisoning. Silymarin prevents uptake of the poison into the cells of the liver and thus
prevent the lethal liver damage associated with this type of mushroom poisoning. Silymarin is regularly used for an assortment of liver diseases including cirrhosis and viral hepatitis in humans.
SIDE EFFECTS Milk
thistle extracts appear to be safe. Side effects are very rare but the following has been reported for humans: upset stomach,
headache, joint pain, weakness. INTERACTIONS WITH OTHER
DRUGS There are no known drug interactions. Caution should be used if you
are taking:
a. Oral contraceptives: Milk thistle may reduce their
effectiveness.
Interactions With Herbs And Dietary Supplements: Milk thistle may lower blood sugar levels. People using
other herbs or supplements that may affect blood sugar levels, such as bitter melon (Momordica charantia), should be monitored
closely by their health care provider while using milk thistle. Dosing adjustments may be necessary. CONCERNS AND CAUTIONS WARNING: Pregnant or lactating women should consult a doctor before using any product. Avoid this product if
you are allergic to ragweed or daisy-like flowers. Discontinue use and consult your doctor if any adverse reactions or allergic
reactions occur. NOT INTENDED FOR USE BY PERSONS UNDER THE AGE OF 18. KEEP OUT OF REACH OF CHILDREN. STORE IN A DRY PLACE
AND AVOID EXCESSIVE HEAT. Silymarin is not recommended for humans during pregnancy. Milk thistle products should be stored
at room temperature.
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